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KMID : 0861020080230020193
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Korea Journal of Herbology
2008 Volume.23 No. 2 p.193 ~ p.202
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A Study on the Antioxidative and Depigmentation Activities of the Ethanol Extract of Saururus Herba
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Park Dae-Jung
Lee Jang-Cheon
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Abstract
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Objectives: The purpose of this study is to investigate the etahnol extract of Saururus Herba and their dermal boiactivity properties related to cosmeceuticals such as depigmentation and radical scavenging effect.
Methods: Using B16/F10 Melanin cells, we measured depigmentation effect of the etahnol extract of Saururus Herba. Antioxidant activities of the etahnol extract of Saururus Herba were determined by DPPH radical scavenging activity.
Results: The etahnol extract of Saururus Herba showed considerable radical scavenging activity(SC50 : 25 ㎍/㎖). Antioxidant activity is in a dose dependant manner. The etahnol extract of Saururus Herba down-regulated melanin synthesis effectively. B16 cells incubated with the etahnol extract of Saururus Herba showed reduces melanin formation and tyrosinase activity. The etahnol extract of Saururus Herba alone markedly suppressed melanin content and tyrosinase activity.
Conclusions: These results suggest that the ethanol extract of Saururus Herba is a potent depigmentaion agent and it may be a candidate for antioxidant agent.
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KEYWORD
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Saururus Herba, Antioxidative, Depigmentation
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